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Bipedalism and Brain Expansion Explain Why Most Humans Are Right‑Handed

A cross-species analysis finds upright walking followed by brain growth drove the shift to a population-level right-hand bias.

Overview

  • The peer-reviewed study, published in PLOS Biology, tested multiple theories and found that two traits best account for humans’ strong rightward bias: a shift to walking on two legs and later increases in brain size and reorganization.
  • Researchers combined a meta-analysis with phylogenetic comparative models using data from 2,025 individuals across 41 monkey and ape species to control for shared evolutionary history and compare competing explanations.
  • Model reconstructions project a gradual strengthening of right-hand preference through the Homo lineage — weak bias in Ardipithecus and Australopithecus rising in H. ergaster and H. erectus and peaking in H. sapiens — with Homo floresiensis as a notable outlier.
  • The paper leaves key questions open: roughly 10% of people are left-handed, and the roles of rare genetic variants, prenatal brain asymmetry, and cultural forces in maintaining or amplifying left-handedness remain unresolved.
  • The study’s method offers a roadmap for future work by linking anatomy and behavior across species and by encouraging tests of similar limb-preference patterns in other animals and more detailed genetic and developmental studies in humans.