Overview
- Ugur Sahin and Özlem Türeci will leave by year-end to lead an independent company focused on next‑generation mRNA medicines.
- BioNTech will transfer certain mRNA technologies and related rights to the new firm in return for minority equity and contingent payments.
- The supervisory board has begun a search to appoint successors for the CEO and chief medical officer roles.
- BioNTech posted a Q4 2025 net loss of €305 million on €907.4 million in revenue and guided 2026 revenue to €2.0–€2.3 billion, below analyst expectations, with lower Comirnaty sales anticipated in the U.S. and Europe.
- Shares fell roughly 14%–20% on Tuesday after the announcements, as the company emphasized an oncology pivot with 15 late‑stage trials targeted by year‑end and a goal of becoming a multi‑product company by 2030.