Overview
- Adium has begun market availability in December with 2.5 mg and 5 mg prefilled pens, with higher-dose presentations expected next year.
- ANMAT authorizes use for adults with obesity (BMI ≥30) or overweight with comorbidity (BMI ≥27) and for type 2 diabetes, given once weekly in stepped doses from 2.5 mg to 15 mg.
- SURMOUNT and SURPASS studies reported approximately 25–26% weight loss and additional improvements in waist circumference, blood pressure, triglycerides and fatty liver.
- The most common adverse effects are gastrointestinal symptoms such as nausea, vomiting and diarrhea, which clinicians report typically ease over time.
- Retail pricing is high, with a four-dose 5 mg pack listed at ARS 783,858.40, and Adium says patients with prescriptions may receive discounts of up to about 30%.