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Angelini Pharma to Acquire Catalyst Pharmaceuticals for $4.1 Billion in Cash

The all-cash deal gives the Italian group a U.S. foothold to scale a Brain Health–focused rare-disease platform.

Overview

  • Angelini Pharma and Catalyst announced a definitive deal Thursday that both boards approved to take Catalyst private at an equity value of about $4.1 billion.
  • Angelini will pay $31.50 per share in cash, a 21% premium to Catalyst’s April 22 unaffected close and 28% above the 30-day average price.
  • Blackstone funds will participate in the financing, with BNP Paribas serving as sole global coordinator and underwriter.
  • Angelini says it plans to fold Catalyst’s approved drugs—Firdapse for Lambert–Eaton myasthenic syndrome, Agamree for Duchenne muscular dystrophy, and U.S. rights to the epilepsy drug Fycompa—into a broader Brain Health portfolio.
  • The companies expect to close in the third quarter of 2026 pending Catalyst stockholder and regulatory approvals, with reports noting a recent Firdapse patent dispute resolution and an earnings report due May 11.