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Amy Schumer Says 'Botched Colonoscopy' Has Left Her Not Feeling Very Sexual

The disclosure at a live podcast event underscores her ongoing openness about health and life changes.

Overview

  • Schumer, speaking at a Not Skinny But Not Fat live event on Sunday, said a botched colonoscopy has left her with low sexual desire.
  • She offered no medical details, and a colonoscopy is a camera exam of the large intestine used to screen for colorectal cancer starting at age 45.
  • She added that she feels happier than ever, as she navigates a December 2025 split from Chris Fischer and a January 2026 uncontested divorce filing.
  • The remark extends prior health disclosures, including a 2024 diagnosis of exogenous Cushing syndrome that she linked to steroid injections and a 2021 surgery that removed her uterus and appendix for endometriosis.
  • She has also discussed trying GLP-1 weight-loss drugs and using telehealth-prescribed estrogen and progesterone for perimenopause symptoms, which she said boosted her energy and mood.