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Alphabet Seeks EPA Permission to Release 32 Million Sterile Mosquitoes

EPA review will decide whether automated Wolbachia‑infected male releases can be scaled to curb disease‑carrying Aedes aegypti.

Overview

  • The Debug project has applied for an EPA experimental use permit to release up to 16 million lab‑bred, Wolbachia‑infected male mosquitoes per state per year in California and Florida for two years, totaling 32 million.
  • The released males are infected with a naturally occurring bacterium called Wolbachia that makes their matings with wild females produce nonviable eggs, and males do not bite humans.
  • The EPA is accepting public comments through June 5 as it evaluates the application and any operational conditions that would govern a trial; no locations, start dates, or formal approvals have been announced.
  • Debug cites prior local trials and overseas programs that reported large local mosquito declines, while experts and vector districts caution that scaling, cost, repeated releases, male–female separation and dormant eggs remain technical challenges.
  • The proposal has drawn political and public pushback over ecological risk and corporate oversight even as public‑health proponents say targeting the invasive Aedes aegypti could lower disease risk in parts of California and Florida.