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2d ago

49ers Add Christian McCaffrey to Injury Report With Back Issue, List Him as Questionable vs. Titans

The late designation follows a full practice Friday after an earlier illness.

12/12/2025
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Defensive coordinator Robert Saleh celebrates with the defense after a missed field goal in the second half as the 49ers played the Carolina Panthers at Levi’s Stadium on Nov. 24. The 49ers defeated the Panthers 20-9.
Niners wide receiver Ricky Pearsall, catching a pass against Jalen Thompson of the Arizona Cardinals on Sept. 21, had 20 catches for 327 yards in four games before missing six games with knee discomfort.

Overview

  • San Francisco placed McCaffrey on the Week 15 injury report Saturday with a back injury, listing him as questionable for Tennessee.
  • Team reports two days earlier had him as a full participant and cleared to play, indicating a sharp late-week shift.
  • ESPN’s Adam Schefter reported McCaffrey is still expected to be “good to go,” though his final status will be set with Sunday’s inactives.
  • The 49ers enter at 9-4 hosting the 2-11 Titans at Levi’s Stadium, with sportsbooks holding San Francisco as roughly a 12.5-point favorite.
  • Tennessee travels with offensive line concerns as Lloyd Cushenberry, Dan Moore Jr., and Kevin Zeitler were listed questionable, while Brian Robinson Jr. is the likely lead back if McCaffrey cannot play.